S1: Mutations are random changes to the base sequence of genes. S6: Several mutations must occur in the same cell for it to become a tumour cell. P: This is why mutations in them can result in uncontrolled cell division and therefore tumour formation. Q: The few genes that can become cancer-causing after mutating are known as oncogenes. R: Most genes do not cause cancer if they mutate. S: In a normal cell oncogenes are involved in the control of cell cycle and cell division.

Directions: In this section each item consists of six sentences of a passage. The first and sixth sentences are given in the beginning as S1 and S6. The middle four sentences in each have been jumbled up and labelled as P, Q, R and S. You are required to find the <strong>PROPER SEQUENCE</strong> of the four sentences and mark your response accordingly on the answer sheet.

  1. A. RQSP ✓
  2. B. QRSP
  3. C. QSRP
  4. D. RPQS

Correct Answer: A. RQSP

Explanation

R follows S1 by clarifying that most mutations don't cause cancer. Q introduces the few that do (oncogenes). S explains their normal function, and P explains the consequence of their mutation.

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